Neuromuscular Blocking Agents or Muscle Relaxants.

(Part 8, Drugs acting on CNS, VPT)

Topic: Drugs acting on Somatic Nervous System - Muscle Relaxants.(According to the syllabus of VCI this Topic is under Unit 3, Drugs acting on CNS but you have to know Muscle Relaxants are the drugs which are acting on Somatic Nervous System)

Neuromuscular Blocking Agents or Muscle Relaxants

Neuromuscular Blocking Agents


Neuromuscular blocking agents act by interfering with the effectiveness of acetyl choline (Ach) to activate nicotinic cholinergic receptors of skeletal muscle cells. This results in skeletal muscle paralysis and muscular relaxation.

The main clinical use of the neuromuscular blocking agents is obtain relaxation of skeletal muscle, particularly of the abdominal wall, so that operative manipulations are facilitated during surgery. Normally it is use to avoid the side effect or unwanted consequence of Anaesthetics.
Note: The following pdf is the VPT note of Drugs acting on CNSPart 8 of BVSc & AH. *VPT- Veterinary Pharmacology and Toxicology.

Topics of the PDF file of 'Neuromuscular Blocking Agents or Muscle Relaxants':

History / Classification of Muscle Relaxants / Nicotinic Cholinergic Receptor / Pharmacological Properties or Mechanism of action of Muscle Relaxants / Therapeutic uses of Neuro Muscular Blocking Agents / Centrally and Peripherally acting Muscle Relaxants.

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Previous VPT notes of 'Drugs acting on Central Nervous System' are AnaesthesiaAnastheticsHypnotics & SedativesPsychotropic DrugsAnalgesics DrugsCNS Stimulants and Drugs acting on Somatic Nervous System - Local Anaesthetics etc. Hope the note will benefited you. Share with your Vet Friends and Family. For any query knock us. Stay tuned. Thank You. Happy Learning!

Veterinary Pharmacology and Toxicology